10 Best Acne Spot Treatments to Zap Problem Zits FAST

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When I worked in the skincare industry many of my clients who suffered from acne would complain to me that although they stuck to their daily skin care regimen religiously – cleanse, exfoliate, and moisturize – they still would experience the occasional monster breakout.

You know the kind, large, red pimples that seemingly appear out of nowhere and are pretty much impossible to ignore.

The truth is, sometimes having an established routine is simply not enough and in instances like this, it is crucial to have a secret weapon on hand – cue the best acne spot treatments!  

A spot treatment contains highly concentrated levels of good-for-you skin nutrients as well as acne ass kicking ingredients that attack specific trouble spots on the face.

The beauty of a spot treatment is, you can zap your zit with a powerful treatment without drying out or irritating the rest of the face.

Spot treatments also work great for those who don’t suffer from acne but experience the occasional breakout.

If you don’t already own one, we definitely recommend reading below to discover some of the absolute best acne spot treatments on the market!

the best acne spot treatments

Mario Badescu Glass Bottle Drying Lotion

Mario Badescu Drying Lotion, 1 Fl Oz

This cult favorite fast drying lotion is the perfect acne spot treatment for anyone who is looking for overnight results.

It is formulated with salicylic acid and calamine to minimize whiteheads and pimples fast.

Recommended for all skin types, this lotion is a great value for drying up blemishes and contains natural ingredients which help to pull out impurities from the skin.

TreeActiv Cystic Acne Spot Treatment

TreeActiv Cystic Acne Spot Treatment, Extra Strength Fast Acting Formula for Clearing Severe Acne from Face and Body, Gentle Enough for Sensitive Skin, Adults, Teens, Men, Women (0.25oz)

Designed for severe and cystic acne, TreeActiv Cystic Acne Spot Treatment is packed with all natural ingredients that calm the skin and get rid of acne from within.

Bentonite Clay, Witch Hazel, Tea tree oil, and pink grapefruit essential oil work together to reduce inflammation, kill bacteria, and prevent future breakouts by balancing oil production.

This product is great for anyone who experiences cystic acne not only because of it’s amazing ability to clear skin, but also because the Bentonite Clay and pink grapefruit essential oil helps to calm inflammation and soothe irritated skin.

BOSCIA Clear Complexion Willow Bark Spot Treatment

If you have sensitive skin, give this botanical-based spot treatment by Boscia a try.

Relying on the super gentle healing powers of botanical willow bark to calm against inflammation, this product also contains soapberry peel to help purify and clean the skin.

Lastly, jojoba leaf and Vitamins C and E all aid in combating redness, oiliness, maintaining a clear complexion, and protecting the skin from free radicals.

ACT! Acne and Blemish Treatment Gel

Although a little pricey, this product has earned it’s spot on this Best Spot Treatments list for several reasons!

First, it’s cruelty free, organic, and vegan! Also, it relies on salicylic acid to exfoliate dead skin and clear pores, so it’s great for those who dislike benzoyl peroxide.

One final pro? It contains tea tree oil and witch hazel, the former of which helps reduce inflammation and smooth out bumps, while the latter controls oil.

Neutrogena Rapid Clear Acne Eliminating Spot Gel With Salicylic Acid

Neutrogena Rapid Clear Acne Eliminating Spot Treatment Gel with Witch Hazel and Salicylic Acid Acne Medicine for Acne-Prone Skin, 0.5 fl. oz (Pack of 3)

Experience breakouts that get out of hand fast? If you answered “yes” then you need this spot treatment from Neutrogena!

This product is clinically proven to reduce a pimple’s redness, size, and swelling in 8 hours!

By using MICROCLEAR Technology, this product is able to boost the performance of acne medication and ensure it gets down into congested pores for optimal results.

Peter Thomas Roth Acne-Clear Invisible Dots

Peter Thomas Roth Acne-clear Invisible Dots

These invisible dots adhere to the skin and clear up blemishes and blackheads with salicylic acid.

These dots also contain tea tree oil to refresh the skin and hyaluronic acid to prevent the skin from drying out.

The only con we found with these dots is that they seem to work most effectively on smaller blemishes and not larger cysts.

BURT’S BEES Natural Acne Solutions Targeted Spot Treatment

Burt's Bees Natural Acne Solutions Targeted Spot Treatment for Oily Skin, 0.26 Ounces

This spot treatment is 100% natural and contains ingredients like tea tree and calendula to help soothe skin and reduce redness.

With salicylic acid, you can expect cleaner pores and a reduction in current and future breakouts.

Murad Acne Spot Treatment

Another option that doesn’t have any benzoyl peroxide, this spot treatment contains ingredients such as sulfur, zinc oxide, salicylic acid, and licorice extract to name a few.

The sulfur is great for those who have sensitive skin but still want a powerful cream for pesky pimples.

The zinc oxide and licorice help to soothe the skin and calm against inflammation, while the salicylic acid exfoliates and speeds up the healing process.

Clean & Clear Advantage Acne Spot Treatment

By far the most budget friendly option on this list, this spot treatment contains salicylic acid and oil absorbing technology that allows the acne medication to penetrate the pores more effectively.

This product also contains an oil-free formula and won’t dry out the skin.

Elements of Beauty Unblemished Spot Treatment

Unblemished Acne Spot Treatment by Elements of Beauty - Best Skin Care Acne Removal Treatment: Reduce Blemishes - Natural Acne Treatment - Acne Cream - Salicylic Acid, Retinol, Niacinamide

This spot treatment gets bonus points for it’s ability to also function as a mask! Salicylic acid helps to clear up blemishes and blackheads, while lavender essential oil and aloe vera clean out pores.

Those who swear by it love it’s scent, texture, and ability to not only clear up blemishes, but fade marks as well.


What do you do and/or use to get rid of pimples fast?

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